The Unified Algorithm for Detection of Potential Lesions in Dynamic Perfusion Maps Cerebral Blood Flow, Cerebral Blood Volume and Time to Peek

This paper presents an unified algorithm that enables detection of lesions in cerebral blood flow (CBF), cerebral blood volume (CBV) and time to peek (TTP) perfusion maps. The algorithm has one adaptive parameter for each type of perfusion map, the rest of algorithm is common for all kinds of perfusion images. There are two steps of the algorithm: in the first step the algorithm detects symmetry axis of a perfusion map (between left and right hemisphere), in the second stage the level of asymmetry in cerebral blood flow, cerebral blood volume or time to peak is measured by detection of regions with different perfusion in both brain hemispheres. Test of the algorithm were performed on a set of 84 different CBF, CBV and TTP images showing or not cerebral blood flow and volume anomalies. The algorithm presented in this publication has achieved satisfactory results. On 85,7% maps asymmetry regions was properly detected.